Ludwig R, Schubert AD, Barbatei D, Bauwens L, Hoffmann JM, Werlen S, Elicin O, Dettmer M, Zrounba P, Pouymayou B, Balermpas P, Grégoire V, Giger R, Unkelbach J. Modelling the lymphatic metastatic progression pathways of OPSCC from multi-institutional datasets. Sci Rep. 14(1):15750, 2024
Torelli N, Bicker Y, Marc L, Fabiano S, Unkelbach J. A new approach to combined proton-photon therapy for metastatic cancer patients. Phys Med Biol. 69(14), 2024
Ludwig R, Werlen S, Barbatei D, Widmer L, Pouymayou B, Balermpas P, Elicin O, Dettmer M, Zrounba P, Giger R, Grégoire V, Schubert A, Unkelbach J. Patterns of lymph node involvement for oral cavity squamous cell carcinoma. Radiotherapy & Oncology, 2024 (in print)
2023
Y Pérez Haas, R Ludwig, R Dal Bello, S Tanadini-Lang, J Unkelbach. Adaptive fractionation at the MR-Linac, Phys. Med. Biol. 19;68(3):035003, doi: 10.1088/1361-6560/acafd4, 2023
N. Torelli, D. Papp, J. Unkelbach. Spatiotemporal fractionation schemes for stereotactic radiosurgery of multiple brain metastases. Medical physics, 50(8):5095-5114,2023
2022
S. Fabiano, N. Torelli, D. Papp, J. Unkelbach. A novel stochastic optimization method for handling misalignments of proton and photon doses in combined treatments, Phys. Med. Biol. 67(18), 2022
R. Ludwig, J. Hoffmann, B. Pouymayou, G. Morand, M. Broglie Däppen, M. Guckenberger, V. Grégoire, P. Balermpas, J. Unkelbach. A dataset on patient-individual lymph node involvement in oropharyngeal squamous cell carcinoma. Data in Brief, 43:p108345, 2022
F. Amstutz, S. Fabiano, L. Marc, D. Weber, A. Lomax, J. Unkelbach, Y. Zhang. Combined proton‐photon therapy for non‐small cell lung cancer, Medical Physics, 49(8):5374-5386, 2022
D. Papp, J. Unkelbach. Optimal allocation of limited proton therapy resources using model‐based patient selection, Medical Physics, 49(8):4980-4987, 2022
R. Ludwig, J. Hoffmann, B. Pouymayou, M. Broglie Däppen, G. Morand, M. Guckenberger, V. Grégoire, P. Balermpas; J. Unkelbach. Detailed patient-individual reporting of lymph node involvement in oropharyngeal squamous cell carcinoma with an online interface. Radiotherapy & Oncology, 169:p1-7, 2022
J. Unkelbach, S. Fabiano, ABA. Bennan, S. Müller, M. Bangert. Joint optimization of radiotherapy treatments involving multiple radiation modalities. IEEE Transactions on Radiation and Plasma Medical Sciences, 6(3):p294-303, 2022
M. Lapaeva, A. La Greca Saint-Esteven, P. Wallimann, M. Günther, E. Konukoglu, N. Andratschke, M. Guckenberger, S. Tanadini-Lang, R. Dal Bello. Synthetic computed tomography for low-field magnetic resonance-guided radiotherapy in the abdomen. Phys Imaging Radiat Oncol. 2022 Nov 28;24:173-179
2021
L. Marc, S. Fabiano, N. Wahl, C. Linsenmeier, A. Lomax, J. Unkelbach. Combined proton-photon treatment for breast cancer. Phys. Med. Biol., 66(23):235002, 2021
D. Vuong, M. Bogowicz, L. Wee, O. Riesterer, E. Vlaskou Badra, L. Abigail D’Cruz, P. Balermpas, J. van Timmeren, S. Burgermeister, A. Dekker, D. De Ruysscher, J. Unkelbach, S. Thierstein, E. I. Eboulet, S. Peters, M. Pless, M. Guckenberger, S. Tanadini-Lang. Quantification of the spatial distribution of primary tumors in the lung to develop new prognostic biomarkers for locally advanced NSCLC. Scientific Reports, 11(1):p1-10, 2021
R. Ludwig, B. Pouymayou, P. Balermpas, J. Unkelbach. A hidden Markov model for lymphatic tumor progression in the head & neck. Scientific Reports, 11(1):p1-17, 2021
F. Amstutz, L. Nenoff, F. Albertini, CO. Ribeiro, AC. Knopf, J. Unkelbach, DC. Weber, AJ. Lomax, Y. Zhang. An approach for estimating dosimetric uncertainties in deformable dose accumulation in pencil beam scanning proton therapy for lung cancer, Phys. Med. Biol. 66:105007, 2021
ABA. Bennan, J. Unkelbach, N. Wahl, P. Salmone, M. Bangert. Joint Optimization of Photon-Carbon ion treatments for Glioblastoma. Int. J. Rad. Onc. Biol. Phys., 111(2):p559-572, 2021
N. Loizeau, S. Fabiano, D. Papp, K. Stützer, A. Jakobi, A. Bandurska-Luque, E. Troost, C. Richter, J. Unkelbach. Optimal allocation of proton therapy slots in combined proton-photon radiotherapy. Int. J. Rad. Onc. Biol. Phys., 111(1):p196-207 , 2021
2020
D. Vuong, M. Bogowicz, S. Denzler, C. Oliveira, R. Foerster, F. Amstutz, HS. Gabryś, J. Unkelbach, et al. Comparison of robust to standardized CT radiomics models to predict overall survival for non‐small cell lung cancer patients. Med. Phys. 47(9):p4045-4053, 2020
I. Telarovic, J. Krayenbuehl, I. Grgic, F. Tschanz, M. Guckenberger, M. Pruschy, J. Unkelbach. Probing spatiotemporal fractionation on the preclinical level. Phys. Med. Biol. 65(22):22NT02, 2020
Fabiano S, Balermpas P, Guckenberger M, Unkelbach J. Combined proton-photon treatments - A new approach to proton therapy without a gantry. Radiotherapy & Oncology. 2020; 145:81-87
Fabiano S, Bangert M, Guckenberger M, Unkelbach J. Accounting for range uncertainties in the optimization of combined proton-photon treatments via stochastic optimization. Int J Radiat Oncol Biol Phys. 2020 Apr 30:S0360-3016(20)31055-5
M Bogowicz, A Jochems, TM Deist, et al. Privacy-preserving distributed learning of radiomics to predict overall survival and HPV status in head and neck cancer, Scientific reports 10 (1), 1-10, 2020
J. Unkelbach, T. Bortfeld, et al. The role of computational methods for automating and improving clinical target volume definition. Radiotherapy and Oncology, in print, 2020
2019
Pouymayou B, Balermpas P, Riesterer O, Guckenberger M, Unkelbach J. A Bayesian network model of lymphatic tumor progression for personalized elective CTV definition in head and neck cancer. Phys Med Biol. 2019, 14;64(16):165003
Pouymayou B, Koechli C, Balermpas P, Guckenberger M, Unkelbach J. Analysis of lymphatic metastasis and progression patterns for clinical target volume (CTV) definition in head and neck squamous cell carcinoma (HNSCC). Acta Oncol. 2019 Oct;58(10):1519-1522
Gaddy MR, Unkelbach J, Papp D. Robust spatiotemporal fractionation schemes in the presence of patient setup uncertainty. Med. Phys. 2019 Jul;46(7):2988-3000
Ehrbar S, Jöhl A, Kühni M, Meboldt M, Ozkan Elsen E, Tanner C, Goksel O, Klöck S, Unkelbach J, Guckenberger M, Tanadini-Lang S. Dynamically deformable liver phantom for real-time motion-adaptive radiotherapy treatments. Med Phys. 2019 Feb;46(2):839-850
Vuong D, Tanadini-Lang S, Huellner MW, Veit-Haibach P, Unkelbach J, Andratschke N, Kraft J, Guckenberger M, Bogowicz M. Interchangeability of radiomic features between [18F]-FDG PET/CT and [18F]-FDG PET/MR. Med Phys. 2019 Apr;46(4):1677-1685
2018
Unkelbach J, Bangert M, De Amorim Bernstein K, Andratschke N, Guckenberger M. Optimization of combined proton-photon treatments. Radiother Oncol, 128(1):133-138, 2018
J. Unkelbach, Alber M, Bangert M, Bokrantz R, Chan TCY, Deasy JO, Fredriksson A, Gorissen BL, van Herk M, Liu W, Mahmoudzadeh H, Nohadani O, Siebers JV, Witte M, Xu H. Robust Radiotherapy Planning. Phys. Med. Biol., 63(22):22TR02, 2018
Gaddy MR, Yıldız S, Unkelbach J, Papp D. Optimization of spatiotemporally fractionated radiotherapy treatments with bounds on the achievable benefit. Phys. Med. Biol., 63(1):015036, 2018
Tanadini-Lang, S., Bogowicz, M., Veit-Haibach, P., Huellner, M., Pauli, C., Shukla, V., Guckenberger, M., & Riesterer, O. (2018). Exploratory Radiomics in Computed Tomography Perfusion of Prostate Cancer. Anticancer Res, 38(2), 685-690. doi:10.21873/anticanres.12273
Pavic, M., Bogowicz, M., Würms, X., Glatz, S., Finazzi, T., Riesterer, O., Roesch, J., Rudofsky, L., Friess, M., Veit-Haibach, P., Huellner, M., Opitz, I., Weder, W., Frauenfelder, T., Guckenberger, M., & Tanadini-Lang, S. (2018). Influence of inter-observer delineation variability on radiomics stability in different tumor sites. Acta Oncologica, 1-5. doi:10.1080/0284186X.2018.1445283
Leijenaar, R. T., Bogowicz, M., Jochems, A., Hoebers, F. J., Wesseling, F. W., Huang, S. H., Chan, B., Waldron, J. N., O'Sullivan, B., Rietveld, D., Leemans, C. R., Brakenhoff, R. H., Riesterer, O., Tanadini-Lang, S., Guckenberger, M., Ikenberg, K., & Lambin, P. (2018). Development and validation of a radiomic signature to predict HPV (p16) status from standard CT imaging: a multicenter study. The British Journal of Radiology, 0(0), 20170498. doi:10.1259/bjr.20170498
L Basler, N Andratschke, S Ehrbar, M Guckenberger and S Tanadini-Lang. Modelling the immunosuppressive effect of liver SBRT by simulating the dose to circulating lymphocytes: in-silico planning study. Radiation Oncology, vol. 13, no. 1, p. 10, 2018.
J. Unkelbach, H. Paganetti. Robust Proton Treatment Planning: Physical and Biological Optimization. Seminars in Radiation Oncology, 28(2):88-96, 2018
2017
Bogowicz M, Leijenaar RTH, Tanadini-Lang S, Riesterer O, Pruschy M, Studer G, Unkelbach J, Guckenberger M, Konukoglu E, Lambin P. Post-radiochemotherapy PET radiomics in head and neck cancer - The influence of radiomics implementation on the reproducibility of local control tumor models. Radiother Oncol. 2017 Dec;125(3):385-391.
Unkelbach J, Papp D, Gaddy MR, Andratschke N, Hong T, Guckenberger M. Spatiotemporal fractionation schemes for liver stereotactic body radiotherapy. Radiother Oncol. 2017 Nov;125(2):357-364
Bogowicz M, Riesterer O, Schneebeli Stark L, Studer G, Unkelbach J, Guckenberger M, Tanadini-Lang S. Comparison of PET and CT radiomics for prediction of local tumor control in head and neck squamous cell carcinoma. Acta Oncol. 2017 Nov;56(11):1531-1536
Bogowicz, M., Riesterer, O., Stark, L. S., Studer, G., Unkelbach, J., Guckenberger, M., & Tanadini-Lang, S. (2017). Comparison of PET and CT radiomics for prediction of local tumor control in head and neck squamous cell carcinoma. Acta Oncol, 56(11), 1531-1536. doi:10.1080/0284186x.2017.1346382
Bogowicz, M., Riesterer, O., Ikenberg, K., Stieb, S., Moch, H., Studer, G., Guckenberger, M., & Tanadini-Lang, S. (2017). Computed Tomography Radiomics Predicts HPV Status and Local Tumor Control After Definitive Radiochemotherapy in Head and Neck Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys, 99(4), 921-928. doi:10.1016/j.ijrobp.2017.06.002
Bogowicz, M., Leijenaar, R. T. H., Tanadini-Lang, S., Riesterer, O., Pruschy, M., Studer, G., Unkelbach, J., Guckenberger, M., Konukoglu, E., & Lambin, P. (2017). Post-radiochemotherapy PET radiomics in head and neck cancer - The influence of radiomics implementation on the reproducibility of local control tumor models. Radiother Oncol, 125(3), 385-391. doi:10.1016/j.radonc.2017.10.023
S Ehrbar, A Jöhl, A Tartas, LS Stark, O Riesterer, S Klöck, M Guckenberger and S Tanadini-Lang. ITV, mid-ventilation, gating or couch tracking - A comparison of respiratory motion-management techniques based on 4D dose calculations. Radiotherapy and Oncology, vol. 124, no. 1, p. 80-88, 2017.
K Karava, S Ehrbar, O Riesterer, J Roesch, S Glatz, S Klöck, M Guckenberger and S Tanadini-Lang. Potential dosimetric benefits of adaptive tumor tracking over the internal target volume concept for stereotactic body radiation therapy of pancreatic cancer. Radiation Oncology, vol. 12, no. 1, p. 175, 2017.
S Ehrbar, S Schmid, A Jöhl, S Klöck, M Guckenberger, O Riesterer and S Tanadini-Lang. Validation of dynamic treatment-couch tracking for prostate SBRT. Medical Physics, vol. 44, no. 6, p. 2466-2477, 2017.
S Ehrbar, S Schmid, A Jöhl, S Klöck, M Guckenberger, O Riesterer and S Tanadini-Lang. Comparison of multi-leaf collimator tracking and treatment-couch tracking during stereotactic body radiation therapy of prostate cancer. Radiotherapy and Oncology, vol. 125, no. 3, p. 445-452, 2017.
A Jöhl, M Bogowicz, S Ehrbar, M Guckenberger, S Klöck, M Meboldt, O Riesterer, M Zeilinger, M Schmid Daners and S Tanadini-Lang. Unconscious physiological response of healthy volunteers to dynamic respiration-synchronized couch motion. Radiation Oncology, vol. 12, no. 1, p. 189, 2017.
2016
M. Bangert, J. Unkelbach. Accelerated iterative beam angle selection in IMRT. Med. Phys., 2016; 43(3):1073-1082
J. Unkelbach, M. Bussière, P. Chapman, J. Loeffler, H. Shih. Spatiotemporal Fractionation Schemes for Irradiating Large Cerebral Arteriovenous Malformations. Int. J. Rad. Onc. Biol. Phys., 2016;95(3):1067-1074
S Ehrbar, S Lang, S Stieb, O Riesterer, LS Stark, M Guckenberger and S Klöck. Three-dimensional versus four-dimensional dose calculation for volumetric modulated arc therapy of hypofractionated treatments. Zeitschrift für Mesizinische Physik, vol. 26, no. 1, p. 45-53, 2016.
S Ehrbar, R Perrin, M Peroni, K Bernatowicz, T Parkel, I Pytko, S Klöck, M Guckenberger, S Tanadini-Lang, DC Weber and A Lomax. Respiratory motion-management in stereotactic body radiation therapy for lung cancer - A dosimetric comparison in an anthropomorphic lung phantom (LuCa). Radiotherapy and Oncology, vol. 121, no.2, p. 328-334, 2016.
A Jöhl, S Lang, S Ehrbar, M Guckenberger, S Klöck, M Meboldt, and M Schmid Daners. Modeling and performance evaluation of a robotic treatment couch for tumor tracking. Biomedical Engineering/Biomedizinische Technik, vol. 61, no. 5, p. 557-566, 2016.
J. Unkelbach, P. Botas, D. Giantsoudi, B. Gorissen, H. Paganetti. Reoptimization of intersity-modulated proton therapy plans based on linear energy transfer. Int. J. Rad. Onc. Biol. Phys., 2016;96(5):1097-1106
Bogowicz, M., Riesterer, O., Bundschuh, R. A., Veit-Haibach, P., Hullner, M., Studer, G., Stieb, S., Glatz, S., Pruschy, M., Guckenberger, M., & Tanadini-Lang, S. (2016). Stability of radiomic features in CT perfusion maps. Phys Med Biol, 61(24), 8736-8749. doi:10.1088/1361-6560/61/24/8736
Nesteruk, M., Lang, S., Veit-Haibach, P., Studer, G., Stieb, S., Glatz, S., Hemmatazad, H., Ikenberg, K., Huber, G., Pruschy, M., Guckenberger, M., Klöck, S., & Riesterer, O. (2015). Tumor stage, tumor site and HPV dependent correlation of perfusion CT parameters and [18F]-FDG uptake in head and neck squamous cell carcinoma. Radiotherapy and Oncology, 117(1), 125-131. doi:10.1016/j.radonc.2015.09.026
